

While often considered a recent discovery, proanthocyanidins, a highly specialized group of bioflavonoids, have been extensively studied since the late 1960's for their powerful vascular wall strengthening properties and free radical scavenging activity. Proanthocyanidins are one of the most potent free radical scavengers known, possessing an antioxidant effect up to 50 times more potent then vitamin E and up to 20 times more powerful then vitamin C. Proanthocyanidins also have an affinity for cell membranes, providing nutritional support to reduce capillary permeability and fragility. Although bioflavonoids are widespread in nature, the powerful proanthocyanidin compound is most abundant and available from the bark of the maritime pine and in grape seeds, or pips.
Bilberry extract contains anthocyanidins with visual and vascular enhancing properties. Bilberry reduces visual fatigue and improves light to dark adjustment through its affinity for the rhodopsin-opsin system, the pigment system which mediates both light and dark vision and visual adaptation to dimly lit spaces. In addition, the extract also has potent antioxidant activity, promoting the retina's own enzymatic antioxidant defenses. In the vascular system the anthocyanidin extract supports the integrity of vascular walls by increasing vitamin C levels within cells, decreasing the permeabilizing effect of certain proteolytic/lysosomal enzymes, stabilizing cell membranes, and stimulating the synthesis of collagen and connective ground substance tissue. Billberry offers a safe and natural way to enhance the strength and function of the visual and vascular system.
Grape pips (seeds) are a potent source of proanthocyanidins, or pycnogenols. This grape pip extract contains 92-95% pycnogenols by weight. Jacques Masquelier, Ph.D., who pioneered proanthocyanidin research and coined the term "pycnogenol," used the grape seed extract in his second phas of proanthocyanidin ivestigation.
The term "pycnogenol" originally denoted the generic proanthocyanidin extracts. However, it is now a registered trademark name referring specifically to the maritime pine extract. Pycnogenol contains a minimum of 85% pycnogenols by weight. The maritime pine was the original source of proanthocyanidins studied and researched by Jacques Masquelier, Ph.D.
This is a statement of nutritional support. This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.
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